All Tests

Bile Acids (Total) Blood Test

£99 ✓ In Stock

What's covered in the price: Laboratory-supplied test kit with sample collection materials and prepaid return packaging. Results turnaround varies by test — see the estimated turnaround time shown above.
Results ready within 9 working days

Your sample goes to a UKAS accredited laboratory meeting ISO 15189 standards.

Date of birth required

After you receive your order confirmation email, please reply with your date of birth.

Blood sample
Clinic visit
(phlebotomy charges apply)
CQC registered Accredited UK labs ISO 15189

How it works

Your testing journey

From order to results in four simple steps. Full transparency on where each step happens and what it costs.

1
Medi Test Direct kit delivered by post

Receive your kit by post

Dispatched same working day if ordered before 3pm. Royal Mail Tracked delivery, typically 1–3 working days. 90% of kits arrive within 24 hours.

2
Clinic sample collection

Visit a partner clinic

Book a phlebotomy appointment at one of our 365+ UK partner clinics. Take your kit with you — the phlebotomist will collect your sample using the materials provided.

Phlebotomy fee applies (paid at clinic)
3
Venous blood draw at a clinic

Venous blood draw at a clinic

A trained phlebotomist takes a small blood sample from a vein in your arm using the vacutainers provided in your kit. The appointment takes around 10 minutes.

4
Return sample by prepaid envelope

Return by prepaid envelope

Seal your sample in the biohazard bag provided and drop it in any Royal Mail postbox using the prepaid Tracked 24 envelope. Post Monday–Thursday for best results.

The Total Bile Acids Blood Test measures the level of bile acids in your blood, providing valuable insights into liver health and bile flow. Bile acids are produced by the liver and stored in the gallbladder, where they are released to help digest fats and absorb fat-soluble vitamins. After performing their digestive function in the intestines, most bile acids are reabsorbed and returned to the liver to be used again.

This test is ideal for individuals monitoring liver function as part of their overall health, those with symptoms suggestive of liver or gallbladder problems such as itching, fatigue, or digestive issues, pregnant women being screened for intrahepatic cholestasis of pregnancy (ICP), and anyone requiring investigation of abnormal liver function tests.

Venous Blood Collection Kit

This kit is sent to you and taken to your chosen clinic. The phlebotomist will collect your sample using the materials provided.

  1. 1Vacutainer blood collection tubes
  2. 2Needle and butterfly needle
  3. 3Tourniquet
  4. 4Alcohol swab
  5. 5Cotton wool and gauze
  6. 6Adhesive plaster
  7. 7Biohazard specimen bag
  8. 8Prepaid return envelope (Royal Mail Tracked 24)
  9. 9Laboratory request form
  10. 10Instructions for the phlebotomist
Fasting Required: This test requires fasting for accurate results. You should fast for at least 8–12 hours before your blood sample is collected. During the fasting period, you may drink plain water but should avoid all food, other drinks, and chewing gum. Eating before the test can significantly elevate bile acid levels and affect result interpretation. Timing: A morning blood draw is recommended, as this allows for overnight fasting. If you have your blood collected later in the day, ensure you have fasted for the full 8–12 hours beforehand. Medications: Certain medications can affect bile acid levels, including cholestyramine, ursodeoxycholic acid (UDCA), and some antibiotics. If you are taking any medications, continue them unless advised otherwise by your doctor, but note them when receiving your results. Pregnancy Testing: If you are pregnant and being tested for intrahepatic cholestasis of pregnancy (ICP), your healthcare provider may have specific timing recommendations. ICP is usually tested in the third trimester when symptoms such as itching (particularly on hands and feet) develop. Interpreting Results: Elevated bile acid levels may indicate liver disease, bile duct obstruction, or problems with bile acid circulation. In pregnancy, elevated levels may suggest ICP, which requires medical monitoring. Please discuss your results with your GP or specialist for proper interpretation.

Bile acids are produced by your liver from cholesterol and stored in your gallbladder. When you eat, they are released into the small intestine where they help digest fats and absorb fat-soluble vitamins (A, D, E, and K). After performing their digestive function, approximately 95% of bile acids are reabsorbed in the terminal ileum and returned to the liver via the portal circulation—a process called enterohepatic circulation. What This Test Measures: This test measures the total concentration of all bile acids in your blood. In a healthy liver with normal bile flow, blood levels of bile acids remain low because the liver efficiently extracts and recycles them. When liver function is impaired or bile flow is obstructed, bile acids accumulate in the blood, leading to elevated levels. Elevated Levels May Indicate: Liver disease (hepatitis, cirrhosis, liver failure), bile duct obstruction (gallstones, strictures, tumours), cholestasis (impaired bile flow), intrahepatic cholestasis of pregnancy (ICP), or primary biliary cholangitis. Elevated bile acids can also occur in intestinal bacterial overgrowth or following ileal resection. Intrahepatic Cholestasis of Pregnancy (ICP): This condition occurs in the third trimester and is characterised by intense itching, particularly on the palms and soles. Elevated bile acids in pregnancy can affect the baby and may require early delivery. Bile acid levels above 10 µmol/L are considered elevated in pregnancy, with levels above 40 µmol/L associated with increased risk. Reference Range: Normal fasting bile acid levels are typically below 10 µmol/L. Values above this may require further investigation. Results should be interpreted by a healthcare professional in the context of your symptoms and other liver function tests.

Medical Disclaimer

This test is for screening and information only — it is not a medical diagnosis or professional advice. Please have your results reviewed by a qualified doctor or healthcare provider who can explain what they mean for your personal health situation. If your results show anything outside the normal range, or if you're worried about your health, see your doctor as soon as you can. Don't change any medications or treatments based on these results alone — always talk to your healthcare provider first.

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Four steps to clarity

Pick your panel 01

Pick your panel

Browse over 200 clinically designed test kits and choose the one that fits your goals.

Kit to your door 02

Kit to your door

Everything you need arrives in discreet packaging with step-by-step instructions inside.

Collect your sample 03

Collect your sample

Follow the simple instructions in your kit — whether it's a finger-prick at home or a venous draw at a partner clinic.

Insights delivered 04

Insights delivered

Clear, easy-to-understand results sent to you online with actionable health guidance.

Frequently asked questions

Elevated bile acids can indicate liver disease, bile duct obstruction, or intrahepatic cholestasis of pregnancy (ICP). In pregnancy, ICP causes intense itching and can pose risks to the baby, making bile acid testing important for pregnant women with itching.

Yes. Bile acid levels rise after eating. Fast for 8-12 hours before sample collection for the most accurate result.

Yes. Bile acid testing is the key diagnostic test for ICP (obstetric cholestasis). If pregnant with intense itching (especially palms and soles, worse at night), your midwife or obstetrician may request this test.

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