Smooth Muscle Antibodies Blood Test
£89 ✓ In Stock
Your sample goes to a UKAS accredited laboratory meeting ISO 15189 standards.
After you receive your order confirmation email, please reply with your date of birth.
How it works
Your testing journey
From order to results in four simple steps. Full transparency on where each step happens and what it costs.
Receive your kit by post
Dispatched same working day if ordered before 3pm. Royal Mail Tracked delivery, typically 1–3 working days. 90% of kits arrive within 24 hours.
Visit a partner clinic
Book a phlebotomy appointment at one of our 365+ UK partner clinics. Take your kit with you — the phlebotomist will collect your sample using the materials provided.
Phlebotomy fee applies (paid at clinic)
Venous blood draw at a clinic
A trained phlebotomist takes a small blood sample from a vein in your arm using the vacutainers provided in your kit. The appointment takes around 10 minutes.
Return by prepaid envelope
Seal your sample in the biohazard bag provided and drop it in any Royal Mail postbox using the prepaid Tracked 24 envelope. Post Monday–Thursday for best results.
Venous Blood Collection Kit
This kit is sent to you and taken to your chosen clinic. The phlebotomist will collect your sample using the materials provided.
- 1Vacutainer blood collection tubes
- 2Needle and butterfly needle
- 3Tourniquet
- 4Alcohol swab
- 5Cotton wool and gauze
- 6Adhesive plaster
- 7Biohazard specimen bag
- 8Prepaid return envelope (Royal Mail Tracked 24)
- 9Laboratory request form
- 10Instructions for the phlebotomist
Smooth muscle antibodies (SMA) are autoantibodies that target proteins in smooth muscle cells, which are found in many organs including blood vessels and the digestive tract. These antibodies are primarily associated with autoimmune hepatitis type 1, the most common form of autoimmune hepatitis, where the immune system attacks liver cells. SMA can also be found at low levels in other autoimmune conditions and sometimes in healthy individuals. Testing for smooth muscle antibodies, usually alongside other autoimmune markers such as ANA and liver kidney microsomal antibodies, helps diagnose autoimmune hepatitis and guide treatment decisions to prevent liver damage. Results outside the normal range may need a follow-up with your GP.
This test is for screening and information only — it is not a medical diagnosis or professional advice. Please have your results reviewed by a qualified doctor or healthcare provider who can explain what they mean for your personal health situation. If your results show anything outside the normal range, or if you're worried about your health, see your doctor as soon as you can. Don't change any medications or treatments based on these results alone — always talk to your healthcare provider first.
NO CLINICS, NO QUEUES, NO HASSLE
Four steps to clarity
01
Pick your panel
Browse over 200 clinically designed test kits and choose the one that fits your goals.
02
Kit to your door
Everything you need arrives in discreet packaging with step-by-step instructions inside.
03
Collect your sample
Follow the simple instructions in your kit — whether it's a finger-prick at home or a venous draw at a partner clinic.
04
Insights delivered
Clear, easy-to-understand results sent to you online with actionable health guidance.
Frequently asked questions
Your immune system is producing antibodies against your own tissues. However, low-level positive results are found in 5-15% of healthy people. A positive result alone is not a diagnosis — it must be interpreted alongside symptoms and clinical examination.
Yes. Not everyone with positive autoantibodies develops autoimmune disease. However, some may develop symptoms in future, so the result is useful for monitoring.
No. Autoimmune antibody tests are not affected by food or drink.
Smooth muscle antibodies (SMA) are most strongly associated with autoimmune hepatitis type 1. They can also occur at low levels in viral hepatitis, cirrhosis, and occasionally in healthy people. A positive result, especially at high titre, warrants liver function testing and specialist assessment.
You may also be interested in
Autoantibodies Profile 2 Blood Test
A 5-biomarker venous blood panel covering autoimmunity — ideal for investigating suspected autoimmune conditions.
Results estimated in 10 working days
5 biomarkers
Autoantibodies Profile 1 Blood Test
A 6-biomarker venous blood panel covering autoimmunity — ideal for investigating suspected autoimmune conditions.
Results estimated in 5 working days
6 biomarkers
Islet Cell Antibodies Blood Test
A single-biomarker venous blood test covering autoimmunity — ideal for investigating suspected autoimmune conditions.
Results estimated in 10 working days
Venous collection
Allergy Screen (Essential Foods) Blood Test
An essential food allergy panel testing for the most common food allergens responsible for IgE-mediated reactions — covering the key foods that account for the majority of food allergies in both children and adults.
Results estimated in 2 working days
9 biomarkers