This product is a home blood test kit that measures antibodies against intrinsic factor (a protein required for Vitamin B12 absorption). These antibodies are often linked to pernicious anaemia, a cause of Vitamin B12 deficiency, and can help determine whether an autoimmune process may be interfering with B12 absorption.
Helps differentiate causes of Vitamin B12 deficiency, particularly pernicious anaemia
Useful when B12 levels are low but the cause is unclear
Supports diagnosis by detecting autoimmune antibodies associated with gastric parietal cell dysfunction
Convenient home sample collection with immunoassay testing in certified labs
A positive intrinsic factor antibody result supports, but does not alone confirm, pernicious anaemia
Some patients with pernicious anaemia may not show these antibodies (lower sensitivity)
A negative result does not rule out autoimmune B12 deficiency; further testing may be required
This test is for informational purposes only; diagnosis should be confirmed by a qualified healthcare professional
All samples are analysed by accredited immunology laboratories using validated methods
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Intrinsic factor is produced in the stomach and helps extract vitamin B12 from the foods we eat. Interference in its production or activity can reduce the absorption of vitamin B12. Intrinsic factor antibodies are produced by the immune system. Intrinsic factor is necessary to extract vitamin B12 from the food we eat. Without sufficient intrinsic factor available, vitamin B12 is unabsorbed and the body cannot produce enough red blood cells which leads to the autoimmune condition pernicious anaemia.
